RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
mir-31
RNA ID
MI0000579
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; reporter gene assays
Target
NA
Pathway
NA
PubMed ID
28865712
Title
MicroRNA-31 promotes adverse cardiac remodeling and dysfunction in ischemic heart disease
Year
2017
Function
miR-31 induction after myocardial infarction (MI) is deleterious to cardiac function while its therapeutic inhibition in vivo ameliorates cardiac dysfunction and prevents the development of post-ischemic adverse remodeling.